DEVELOPMENT OF A CLINICAL DIAGNOSIS AND DECISION SUPPORT SYSTEM FOR CHEST RADIOGRAPHY USING CNN

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dc.contributor.author MAGAR, BIPIN THAPA
dc.date.accessioned 2024-06-11T04:10:26Z
dc.date.available 2024-06-11T04:10:26Z
dc.date.issued 2023-03
dc.identifier.uri http://dspace.mist.ac.bd:8080/xmlui/handle/123456789/819
dc.description I would like to express my sincere gratitude to my supervisor, Md. Asadur Rahman, Ph.D., Assistant Professor, Department of Biomedical Engineering, MIST, for his effective guidance and support throughout this research work whenever necessary. My sincere gratitude goes to Colonel Syed Mahfuzur Rahman, the respected Head of the Department, for his persistent guidance and financial allocation that made this research work possible. I also extend my profound appreciation to the Department of Biomedical Engineering, MIST, for their co-operations and for facilitating me with the materials and laboratory resources to carry out my research work. I am also indebted to all the individuals who directly or indirectly helped and supported me with their technical and editorial feedback in carrying out my research work. I want to acknowledge Capt Kumar Shrestha, my fellow companion, for his continuous support and cooperation in the journey of completing my M.Sc. Engineering together. Finally, I would like to acknowledge the continuous love and support from my loving family and friends throughout the journey and am grateful to everyone who has made this M.Sc. thesis a reality. en_US
dc.description.abstract Chest X-ray (CXR) image is a widely used diagnostic tool for various chest diseases. Human interpretation of CXR images, however, has never been always effective. The diagnostic level of the radiologists along with other factors like cognitive ability, experience, fatigue, and other human-dependent factors may impair the diagnostic procedure with missed information, misinterpretation, and requiring more time and cost. Computer-aided analysis of CXR images has already demonstrated its potential over manual or human screening to facilitate rapid, correct, and low-cost diagnosis of chest diseases. Existing computer-aided systems are still not suitable for real-time applications due to limited findings, limited generalizability across wide datasets, and not being computationally and economically affordable as well. Therefore, an efficient Convolution Neural Network (CNN) based computer-aided decision support system, the CXRNet, was developed for the automatic detection of abnormalities from CXR images in a real-time clinical scenario. The proposed CXRNet model is a 16-layered CNN architecture with 5 output classes: Cardiomegaly, COVID, Normal, Pneumonia, and Tuberculosis. This architecture is trained with frontal CXR images obtained from various sources to improve the generalization of the model across multiple datasets. Upon testing the model on three different data distribution conditions (70% training and 30% testing, 80% training and 20% testing, and 90% training and 10% testing), it achieved a state-of-the-art performance with an average accuracy of 95.7%, a precision of 95.3%, a recall of 95.3%, and an f1-score of 95.3% for the multiclass classification task. The proposed CXRNet also demonstrates excellent performance on binary classification tasks with an average accuracy of over 98% for each disease condition. The results obtained from this work outperform several other custom-designed CNN architectures as well as pre-trained models-based architectures like ResNet, VGG, DenseNet, Xception, Inception, etc. Furthermore, with proper testing, validation, and debugging of the model in clinical practice, it can be successfully deployed as a decision support system for radiologists. en_US
dc.language.iso en en_US
dc.publisher Department of Biomedical Engineering, MIST en_US
dc.subject Chest X-ray image, Convolution Neural Network, Clinical Diagnosis, Decision Support System, Multiclass Classification, Binary Classification en_US
dc.title DEVELOPMENT OF A CLINICAL DIAGNOSIS AND DECISION SUPPORT SYSTEM FOR CHEST RADIOGRAPHY USING CNN en_US
dc.type Thesis en_US


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